top of page

Classroom Introduction

Professor's Greetings

Thank you for visiting the website of the Department of Otolaryngology and Head and Neck Surgery at Asahikawa Medical University.

First, let me introduce myself. I was born in Ashoro-cho, Ashoro-gun, Hokkaido, and after graduating from Hakodate La Salle High School, I graduated from Asahikawa Medical University in 1994 as part of the 16th class. After that, I joined our medical department and, under the warm guidance of many seniors, juniors, and staff, I have been working in my current position since January 2024. Although I am not very knowledgeable or talented, I will do my best with my inherent tenacity. Thank you for your cooperation.

Otolaryngology/Head and Neck Surgery literally covers the vast area of the ears, nose, oral cavity, pharynx, larynx, and head and neck. These areas are responsible for many functions necessary for maintaining life and maintaining its quality, such as hearing, balance, smell, taste, breathing, speech, and swallowing. Our role is to treat the wide variety of diseases that occur in this area without impairing these functions as much as possible. To do this requires a great deal of knowledge and skills, and we are studying hard day and night.

Due to the geographical characteristics of our hospital, which covers a vast area covering northern and eastern Hokkaido, it is essential to train specialists who can treat a wide variety of diseases so that treatment can be completed as much as possible for each region. Our department's training program has been created with this in mind, and each affiliated hospital has excellent specialists who are responsible for the medical care of the region. In addition, if highly specialized treatment is required, we will refer you to a university for treatment. In addition to standard surgeries such as cochlear implant surgery and head and neck free reconstruction surgery, our department also performs cutting-edge treatments such as endoscopic otological surgery, endoscopic thyroid surgery, and endoscopic salivary stone surgery. We are constantly updating our knowledge and technology and working hard to provide medical care that satisfies our patients.

Our department is not only focused on clinical practice, but also on research. Immunotherapy for head and neck cancer is currently being adapted to many antitumor drugs, and is continuing to make progress. We have been actively conducting immunological research into head and neck cancer for some time, and have gained a great deal of knowledge that can be applied to treatment in the future. In addition, basic and clinical research into tonsillar focal disease continues to be a theme of our department, and we are proud to be at the top level internationally.

Our department is made up of young staff, but I am proud to say that we have a team of highly motivated and excellent staff members. Together with them, we will operate a department that is highly active in clinical practice and research, and is filled with passion and sincerity. We will work together as a team to make our department a place that will lead the field of otolaryngology and head and neck surgery in the future, so that people will say that Asahikawa Medical University is in the north. We look forward to your continued guidance and encouragement.

Professor, Department of Otolaryngology and Head and Neck Surgery, Asahikawa Medical University

Thank you for visiting the website of the Department of Otolaryngology and Head and Neck Surgery at Asahikawa Medical University.

First, let me introduce myself. I was born in Ashoro-cho, Ashoro-gun, Hokkaido, and after graduating from Hakodate La Salle High School, I graduated from Asahikawa Medical University in 1994 as part of the 16th class. After that, I joined our medical department and, under the warm guidance of many seniors, juniors, and staff, I have been working in my current position since January 2024. Although I am not very knowledgeable or talented, I will do my best with my inherent tenacity. Thank you for your cooperation.

Otolaryngology/Head and Neck Surgery literally covers the vast area of the ears, nose, oral cavity, pharynx, larynx, and head and neck. These areas are responsible for many functions necessary for maintaining life and maintaining its quality, such as hearing, balance, smell, taste, breathing, speech, and swallowing. Our role is to treat the wide variety of diseases that occur in this area without impairing these functions as much as possible. To do this requires a great deal of knowledge and skills, and we are studying hard day and night.

Due to the geographical characteristics of our hospital, which covers a vast area covering northern and eastern Hokkaido, it is essential to train specialists who can treat a wide variety of diseases so that treatment can be completed as much as possible for each region. Our department's training program has been created with this in mind, and each affiliated hospital has excellent specialists who are responsible for the medical care of the region. In addition, if highly specialized treatment is required, we will refer you to a university for treatment. In addition to standard surgeries such as cochlear implant surgery and head and neck free reconstruction surgery, our department also performs cutting-edge treatments such as endoscopic otological surgery, endoscopic thyroid surgery, and endoscopic salivary stone surgery. We are constantly updating our knowledge and technology and working hard to provide medical care that satisfies our patients.

Our department is not only focused on clinical practice, but also on research. Immunotherapy for head and neck cancer is currently being adapted to many antitumor drugs, and is continuing to make progress. We have been actively conducting immunological research into head and neck cancer for some time, and have gained a great deal of knowledge that can be applied to treatment in the future. In addition, basic and clinical research into tonsillar focal disease continues to be a theme of our department, and we are proud to be at the top level internationally.

Our department is made up of young staff, but I am proud to say that we have a team of highly motivated and excellent staff members. Together with them, we will operate a department that is highly active in clinical practice and research, and is filled with passion and sincerity. We will work together as a team to make our department a place that will lead the field of otolaryngology and head and neck surgery in the future, so that people will say that Asahikawa Medical University is in the north. We look forward to your continued guidance and encouragement.

Professor, Department of Otolaryngology and Head and Neck Surgery, Asahikawa Medical University

Our history

集合写真.png

旭川医科大学耳鼻咽喉科学教室は昭和51年10月に、海野徳二初代教授の着任により開設された。平成10年11月に本学第4期卒業生である原渕保明が第二代教授として就任した。開設当初は5名でスタートを切ったが、その後順調に医局員が増加し、現在では総勢70名を越える大所帯となっている。その間、道北、道東のみならず北海道全域にわたり、多くの人材を輩出し、各地域の耳鼻咽喉科診療の中核として機能する体制が整っている。2024年1月1日からは当教室生え抜きの髙原幹が第三代教授となり、臨床、研究、教育全てにおいて、さらなる高みを目指して教室を運営している。

教室は現在(2024年4月)、教授以下、准教授2名、講師2名、講師(学内)1名、助教3名、医員5名、海外留学2名、言語聴覚士2名、医局秘書2名の総勢20名で組織されている。

 

診療の面では聴力改善手術、鼻科手術、口腔咽頭手術、および頭頸部腫瘍手術を精力的に行い、北海道の耳鼻咽喉科診療の中心的役割を担っている。また、高度難聴に対する人工内耳手術、頭頸部癌に対して嚥下や発声機能を温存して治療するための微小血管吻合を用いた遊離再建手術や超選択的化学動注・同時放射線療法などの最先端の治療も行っている。上気道感染症や呼吸生理に関する疾患についても扁桃病巣疾患、睡眠時無呼吸症候群、アレルギー性鼻炎、小児中耳炎を中心に専門外来を開設し、病態解明の研究とその結果に基づいた最新の診療を行っている(診療概要の欄を参照)。

 

研究の面では「研究と臨床は互いにフィードバックするものでなければいけない」という教室の方針のもとで、1. IgA腎症や掌蹠膿疱症の病態解明、2. 頭頸部癌の新たな免疫治療の開発、3. 頭頸部癌の微小環境における病態解明、4. アレルギー性疾患のT細胞応答を中心とした病態解明、5. 好酸球性疾患の病態を上皮系サイトカインを中心に解明などのテーマで日夜研鑽している、などのテーマで日夜研鑽している(研究概要の欄を参照)。

 

関連病院としては、旭川市内のみならず、札幌市、江別市、函館市、苫小牧市、室蘭市、北見市、釧路市、富良野市、稚内市、名寄市、士別市、根室市、紋別市、遠軽町、芽室町、岩内町、雄武町と北海道全域にわたって基幹病院に常勤あるいは非常勤で教室員を派遣し、その地域の耳鼻咽喉科医療に大きく貢献している(関連病院の欄を参照)。

 

海外の研究留学施設としては、アメリカ合衆国のハーバード大学、メイヨー・クリニック(ロチェスター、スコッツデール)、ヴァンダービルト大学(ナッシュビル)、アーカンソー州立大学(リトルロック)、ジョージア・リージェンツ大学癌センター(オーガスタ)、南フロリダ大学モーフィット癌センター(タンパ)、スイスのチューリッヒ小児病院、スウェーデンのカロリンスカ研究所(ストックホルム)に多数の教室員を研究留学させている(研究概要の欄を参照)。

 

教室外活動としては、道内の耳鼻咽喉科医を対象として年に3回、北北海道耳鼻咽喉科懇話会を開催し、最新の知識の獲得と会員の親睦がはかられている。

Otolaryngology/Head and Neck Surgery Staff Introduction

takahara.jpg

Takahara Miki

Professor

Specially Appointed Associate Professor, Department of Advanced Diagnosis and Treatment of Head and Neck Cancer (Concurrent Appointment)

Graduation Year

H6 Graduated from Asahikawa Medical University

Study Abroad

H15-H17 Karolinska Institute, Sweden

Degree related

H16 Doctor of Medicine

Specialist

  • Specialist of the Japanese Society of Otolaryngology Head and Neck Surgery

  • Head and neck cancer specialist, supervising physician

  • Provisional Supervisor for Rhinology Surgery

  • Endocrine Surgery Specialist

  • Asahikawa Medical University Clinical Training Supervisor

  • Otolaryngology Specialist Training Supervisor

Specialized field

  • Head and neck tumors

  • Tonsillar Focal Disease

  • Endoscopic assisted thyroid surgery

  • Endoscopic Sialolith Surgery

Main Affiliated Academic Societies

  • Japan Society of Otolaryngology Head and Neck Surgery

  • Japan Society of Otorhinolaryngology, Allergy and Immunology, and Infectious Diseases

  • Japanese Society of Oral and Pharyngeal Surgery

  • Japan Society of Endocrine Surgery

  • Japan Head and Neck Cancer Society

  • Japan Society for Head and Neck Surgery

  • Japan Rhinologic Society

  • Japan Otological Society

  • Japanese Cancer Association

  • Japanese Society of Clinical Oncology

  • Japanese Society for Immunology

受賞歴

  • 2018 Journal of Dermatology Best Paper Prize受賞

  • 2021 日本耳鼻咽喉科免疫アレルギー感染症学会 学会賞

hayashi.jpg

Tatsuya Hayashi

Associate Professor (Concurrent)
Chief of Surgery

Graduation Year

S61 Graduated from Asahikawa Medical University

 

Study Abroad

H6-H8 Arkansas State University, USA

Degree related

H9 Doctor of Medicine

Specialist

  • Specialist of the Japan Otolaryngological Society

  • Japan Society for Head and Neck Surgery Head and Neck Cancer Specialist System Supervisor

Specialization/ Area of expertise

Pediatric otitis media, Head and neck surgery

kishibe.jpg

Kishibe Kan

Teacher

Graduation Year

Graduated from Asahikawa Medical University in 1999
Graduated from Asahikawa Medical University Graduate School in 2001

Degree related

2001 Doctor of Medicine (Graduate School of Medicine)

Specialist

Specialist of the Japan Otolaryngological Society

Specialization/ Area of expertise

Dizziness, head and neck tumors

kumai_takumi.jpg

Takumi Kumai

Specially appointed lecturer in the Department of Advanced Diagnosis and Treatment of Head and Neck Cancer (concurrent post)

Graduation Year

Graduated from Asahikawa Medical University in 2008
Graduated from Asahikawa Medical University Graduate School in 2014

Study Abroad

H26-28 Georgia Cancer Institute, Augusta University, USA

Degree related

Doctor of Medicine (Graduate School of Medicine) 2014

Specialist

  • Specialist of the Japan Otolaryngological Society

  • Japanese Society of Allergology Supervisor

  • Certified cancer treatment doctor

  • Japan Society for Head and Neck Surgery Head and Neck Cancer Specialist


Specialized field

allergy

 

Specialty

Head and neck tumors

Rewards and Punishments

  • Asahikawa Medical University, Department of Otolaryngology-Head and Neck Surgery, Alumni Association Academic Encouragement Award, 2014

  • H27 Asahikawa Medical University, Department of Otolaryngology-Head and Neck Surgery, Alumni Association Academic Encouragement Award

  • R1 Research Encouragement Award, 121st Annual Meeting of the Japanese Society of Otolaryngology

  • R4 42nd Japan Academy of Nursing Science Academic Conference Best Poster Presentation Award

  • R5 Asahikawa Medical University Academic Research Award

  • R6 Japan Society of Otorhinolaryngology, Allergy and Immunology, Infectious Diseases Award

Kenzo_wix.jpg

Ohara Kenzo

Teacher

Graduation Year

Graduated from Asahikawa Medical University in 2008
Graduated from Asahikawa Medical University Graduate School in 2018

Study Abroad

April-October 2019 Mayo Clinic, Minnesota, USA
H31/10-R3 Mayo Clinic, Arizona, USA

Degree related

H30 Doctor of Medicine (Graduate School of Medicine)

Specialist

Specialist of the Japan Otolaryngological Society

Specialty

Head and neck cancer

yamaki_hidekiyo.jpg

Ohara Kenzo

Teacher

Graduation Year

Graduated from Asahikawa Medical University in 2008
Graduated from Asahikawa Medical University Graduate School in 2018

Study Abroad

April-October 2019 Mayo Clinic, Minnesota, USA
H31/10-R3 Mayo Clinic, Arizona, USA

Degree related

H30 Doctor of Medicine (Graduate School of Medicine)

Specialist

Specialist of the Japan Otolaryngological Society

Specialty

Head and neck cancer

kohno.jpg

Ohara Kenzo

Teacher

Graduation Year

Graduated from Asahikawa Medical University in 2008
Graduated from Asahikawa Medical University Graduate School in 2018

Study Abroad

April-October 2019 Mayo Clinic, Minnesota, USA
H31/10-R3 Mayo Clinic, Arizona, USA

Degree related

H30 Doctor of Medicine (Graduate School of Medicine)

Specialist

Specialist of the Japan Otolaryngological Society

Specialty

Head and neck cancer

wakisaka.jpg

Ohara Kenzo

Teacher

Graduation Year

Graduated from Asahikawa Medical University in 2008
Graduated from Asahikawa Medical University Graduate School in 2018

Study Abroad

April-October 2019 Mayo Clinic, Minnesota, USA
H31/10-R3 Mayo Clinic, Arizona, USA

Degree related

H30 Doctor of Medicine (Graduate School of Medicine)

Specialist

Specialist of the Japan Otolaryngological Society

Specialty

Head and neck cancer

yamaki_hidekiyo.jpg

Sekine Ichiro

Assistant professor

Graduation Year

Graduated from Asahikawa Medical University in 2014

Specialist

Specialist of the Japan Otolaryngological Society

yamaki_hidekiyo.jpg

Wakisaka Risa

Assistant Professor, Graduate School (BFT)

Graduation Year

Graduated from Asahikawa Medical University in 2016

Specialist

Specialist of the Japanese Society of Otolaryngology Head and Neck Surgery Certified Cancer Treatment Doctor

yamaki_hidekiyo.jpg

Ryota Yuasa

Doctor

Graduation Year

Graduated from Asahikawa Medical University in 2019

Specialist

yamaki_hidekiyo.jpg

Tanaka Kota

Doctor

Graduation Year

R4 Graduated from Asahikawa Medical University

Specialist

yamaki_hidekiyo.jpg

Sato Ryosuke

Assistant Professor, Graduate School (BFT)

Graduation Year

Graduated from Asahikawa Medical University in 2016

Specialist

Specialist of the Japan Otolaryngological Society

yamaki_hidekiyo.jpg

Inoue Takahiro

Medical Officer/Graduate School (BFT)

Graduation Year

Graduated from Asahikawa Medical University in 2019

Specialist

yamaki_hidekiyo.jpg

大湊 久貴 Hisato Ominato M.D.

助教・大学院 BFT

Graduation Year

2018 旭川医科大学卒業

Specialist

日本耳鼻咽喉科頭頸部外科学会専門医

yamaki_hidekiyo.jpg

Hiroki Komatsuda

Assistant Professor, studying abroad

Graduation Year

Graduated from Asahikawa Medical University in 2015

Specialist

Japanese Society of Otolaryngology Head and Neck Surgery Specialist

yamaki_hidekiyo.jpg

Katada Akihiro

Clinical Supervisor Professor

Graduation Year

H4 Graduated from Asahikawa Medical University
H8 Graduated from Asahikawa Medical University Graduate School

Work-related

Asahikawa Red Cross Hospital, Head of Transfusion and Laboratory Department

Study Abroad

H15-17 Department of Otolaryngology, Vanderbilt University, USA

Degree related

H8 Doctor of Medicine (Graduate School of Medicine)

yamaki_hidekiyo.jpg

Bandoh Nobuyuki

Clinical Supervisor Professor

Graduation Year

H4 Graduated from Asahikawa Medical University

Work-related

Vice Director, Hokuto Hospital, Hokuto Social Medical Corporation
Director of Head and Neck Tumor Center
Chief of Otolaryngology and Head and Neck Surgery
Director of Patient Support Center

Study Abroad

2001-2005 Roswell Park Cancer Institute, USA

Degree related

Doctor of Medicine, 2002

yamaki_hidekiyo.jpg

Isamu Kunibe

Clinical Supervisor Professor

Graduation Year

H5 Graduated from Asahikawa Medical University

Work-related

Vice Director, Head and Neck Surgery, Otolaryngology, Sapporo Higashi Tokushukai Hospital

Study Abroad

H17-H20 Department of Otolaryngology, Vanderbilt University, USA

Degree related

H16 Doctor of Medicine

yamaki_hidekiyo.jpg

Katayama Akihiro

Clinical Supervisor Professor

Graduation Year

H6 Graduated from Asahikawa Medical University
H16 Graduated from Asahikawa Medical University Graduate School

Work-related

Sapporo Tokushukai Hospital, Head of Otolaryngology

Study Abroad

H16-H19 Rosewell Park Cancer Institute, USA

Degree related

2004 Doctor of Medicine (Graduate School of Medicine)

yamaki_hidekiyo.jpg

Takashi Gotoh

Clinical Supervisor Professor

Graduation Year

H9 Graduated from Asahikawa Medical University

Work-related

Social Medical Corporation Hokuto Hokuto Hospital Head of Otolaryngology and Head and Neck Surgery Vice Director of Head and Neck Tumor Center

Study Abroad

H20 Doctor of Medicine

Degree related

H20 医学博士

yamaki_hidekiyo.jpg

Yoshizaki Tomoki

臨床指導教授

Graduation Year

Graduated from Asahikawa Medical University in 1990

Work-related

JA Hokkaido Welfare Federation Asahikawa Kosei Hospital Chief of Otolaryngology

Study Abroad

Doctor of Medicine, 2010

Degree related

H22 医学博士

yamaki_hidekiyo.jpg

Nomura Kenichiro

Clinical Supervisor Professor

Graduation Year

Graduated from Asahikawa Medical University in 2001

Work-related

Director of Nomura Otolaryngology Clinic

Study Abroad

H20-22 Department of Otolaryngology, Vanderbilt University, USA

Degree related

Doctor of Medicine, 2011

yamaki_hidekiyo.jpg

Komabayashi Yuhki¥

Clinical Supervisor Professor

Graduation Year

Graduated from Asahikawa Medical University in 2002

Work-related

札幌東徳洲会病院

Study Abroad

Doctor of Medicine, 2014

Degree related

H26 医学博士

Lecturer : Hiroshi Horikawa
Mayumi Tsubakimoto Speech-language-hearing therapist
Katsuki Kyohko Secretary
Fukao NorieSecretary

What we do about basic study

 当教室では耳鼻咽喉科・頭頸部外科領域を幅広く網羅する基礎研究を行っている。また全ての教室員は1つ以上の研究テーマを持ち、研究と臨床を互いにフィードバックさせ、双方のレベルの向上を図っている。毎年、英文学術誌に多くの論文が掲載され、それらの研究成果に対し、国内はもとより国外からも高い評価を受けている。当科で行っている臨床研究に関してはこちらを参照ください。


 また、医局員に対して海外研究留学を積極的に推奨している。2000年度から、アメリカ合衆国のローズウェルパーク癌研究所(バッファロー)、ヴァンダービルト大学(ナッシュビル)、アーカンソー州立大学(リトルロック)、メイヨークリニック(ミネソタ、アリゾナ)、南フロリダ大学モフィット癌センター(タンパ)、ハーバード大学(マサチューセッツ)、スウェーデンのカロリンスカ研究所(ストックホルム)、スイスのチューリッヒ小児病院に延べ18名の教室員を研究留学させている。

I. 免疫アレルギー感染症分野

(高原 幹、熊井琢美、大原賢三、山木英聖、河野通久、脇坂理紗、佐藤遼介、井上貴博)

扁桃病巣疾患の発症機序.jpg

扁桃病巣疾患の病態解明

 扁桃病巣疾患は「扁桃が原病巣となり、扁桃から離れた臓器に反応性の器質的または機能的障害を引き起こす疾患」と定義され、当講座では扁桃摘出術がその症状や所見の改善に有効であることを示してきた。

 

代表的疾患として掌蹠膿疱症、IgA腎症、胸肋鎖骨過形成症が知られており、その病態は不明であったが、当講座をはじめとした近年の基礎研究の進歩により、掌蹠膿疱症ではαレンサ球菌、IgA腎症ではパラインフルエンザ菌や細菌に普遍的に存在するCpG-ODNに対する過剰免疫応答が、扁桃T細胞上の皮膚、腎ホーミング受容体の過剰発現やT細胞非依存性B細胞活性化因子の発現亢進によるIgAの過剰産生を促し、皮膚や腎の病態形成や維持に関与していることが明らかになってきた。

 

さらに、種々の病巣疾患における扁桃摘出術の効果に関して臨床的に検討し、その結果は、扁桃病巣疾患診療の手引きにまとめられている。本研究分野は当科が長年継続して行なっており、我々が先頭に立って牽引してきたものと自負している。また、本邦独自と言える本疾患概念の研究を絶やさないためにも、我々が地道に継続していかなければならない責務を感じている。

II. 腫瘍免疫・血液病態学

(高原 幹、熊井琢美、大原賢三、山木英聖、河野通久、脇坂理紗、佐藤遼介、井上貴博)

Screenshot 2024-07-20 at 9.19.26 PM.png

頭頸部悪性腫瘍について分子腫瘍学的、腫瘍免疫学的およびウイルス学的な多面的解析を行い、将来のがんワクチン、分子標的治療、遺伝子診断・治療を含めたテーラーメイド診療の開発を目指している。

頭頸部癌における新たな免疫治療の開発

 頭頸部癌の標準治療は手術、放射線療法、抗癌剤による集学的治療が主軸であるが、第4の治療法として免疫療法が頭頸部癌においても有用性が示された。免疫チェックポイント阻害薬が頭頸部癌にも適応となったが奏功率は2割前後と満足できるものではなく、より有効な免疫療法の確立が求められている。

 

 免疫チェックポイント阻害薬はその免疫賦活化作用が腫瘍非特異的であることが問題点の一つである。よりT細胞を抗原特異的に増殖させるため、我々はペプチドワクチン療法に着目している。当講座ではこれまでEGFRやHER-3、c-Met、MDM2、p53、FGFR1など頭頸部癌に発現している腫瘍抗原を数多く同定し、その腫瘍抗原から実際に抗腫瘍T細胞を惹起可能なエピトープペプチドの同定を10種類以上行ってきた(右図参照)。

図1.jpg

​  T細胞の増殖にはペプチドによるT細胞受容体刺激(シグナル1)に加えて、共刺激分子(シグナル2)とサイトカイン(シグナル3)による刺激が同時に入る必要がある(下図参照)。当講座ではペプチドワクチンの臨床応用を見据えて、有効な免疫アジュバントの探索とペプチドワクチン療法の開発を目指している。

図2.jpg

III. 免疫・アレルギー病態学
(高原 幹、岸部 幹、熊井琢美、大原賢三、山木英聖、
河野通久、林 隆介、佐藤遼介、脇坂理紗、井上貴博)

シラカンバ花粉症、口腔アレルギー症候群の病態解明と

新規治療法の開発

 当講座では欧米では最も多い花粉症であり、北海道における主要な花粉症であるシラカンバ花粉症に関しても研究を行ってきた。花粉症患者を含めたアレルギー患者数は増加の一途をたどっているが、いまだに根本的な治療法が見出されていないのが現状である。当講座ではアレルギー疾患の新たな治療法の開発とT細胞動態を中心に病態の解明をテーマとして研究を行っている。副鼻腔炎、アレルギー疾患の発症のメカニズムは明らかではなく、好酸球性疾患の病態解明に向けて上皮系サイトカインを中心に解析を行い、臨床的・基礎的検討を重ね解明を進めている。

これまでに当講座ではシラカンバ花粉症における抗原提示細胞についてcDNAアレイを用いて解析し、サイトカイン・ケモカイン産生ならびに共刺激分子発現を健常者と比較検討した。またシラカンバ花粉症に対するペプチドワクチン療法の開発に向けて、シラカンバの抗原エピトープの解析を行い、その一つが抑制性T細胞を誘導可能な事を見出し報告した。

 現在では、近年同定されたTSLP等に代表される新規アレルギーサイトカインに関しての各ヘルパーT細胞サブセットや抗原提示細胞へ及ぼす影響に関する解析も進めている。当科は2008年より日本アレルギー学会認定施設となっており、シラカンバ花粉症患者に高率に合併する口腔アレルギー症候群(oral allergy syndrome:OAS)についての臨床的、基礎的検討も精力的に推し進めていく予定である。

 当講座ではメイヨークリニックへ2名の研究留学経験があり、花粉食物アレルギー症候群(PFAS: pollen food allergy syndrome)の免疫学的機序の解明や気道炎症と神経系のクロストークについても継続して研究を行っている。PFASは花粉抗原と食物抗原の交差反応性によって生じ、原因花粉抗原は シラカバ主要抗原Bet v1が最も多い。現在のPFASの治療は原因食物の回避のみであるが、新規治療法の開発に向けて検討を行っている。

Otolaryngology/Head and Neck Surgery Affiliated Hospitals

旭川厚生病院

日本、北海道旭川市1条通24丁目111

(0166)33-7171

旭川赤十字病院

日本、北海道旭川市曙1条1丁目1−1

(0166)22-8111

市立旭川病院

日本、北海道旭川市金星町1丁目1−65

(0166) 24-3181

JCHO 北海道病院

日本、北海道札幌市豊平区中の島1条8丁目3−18

(011)831-5151

札幌東徳州会病院

日本、北海道札幌市東区北33条東14−3−1

(011)722-1110

札幌徳州会病院

日本、北海道札幌市厚別区大谷地東1丁目1−1

(011)890-1110

恵み野病院

日本、北海道恵庭市恵み野西2丁目3−5

(0123) 36-7555

社会医療法人北斗 北斗病院

日本、北海道帯広市稲田町基線7−5

(0155)48-8000

北見赤十字病院

日本、北海道北見市北6条東2丁目

(0157)24-3115

富良野協会病院

日本、北海道富良野市住吉町1−30

(0167)23-2181

遠軽厚生病院

日本、北海道紋別郡遠軽町大通北3−1−5

(0158)42-4101

市立稚内病院

日本、北海道稚内市中央4丁目11−6

(0162)23-2771

名寄市立総合病院

日本、北海道名寄市西7条南8丁目 1番地

(01654)3-3101

臨生会 吉田病院

日本、北海道名寄市西3条南6丁目8−2

(01654)3-3381

士別市立病院

日本、北海道士別市東11条5丁目3029

(0165)23-2166

広域紋別病院

日本、北海道紋別市落石町1丁目3−37

(0158)24-3111

深川市立病院

日本、北海道深川市6条6−1

(0164)22-1101

日鋼記念病院

日本、北海道室蘭市新富町1−5−13

(0143)24-1331

王子総合病院

日本、北海道苫小牧市若草町3丁目4−8

(0144)32-8111

釧路労災病院

日本、北海道根室市有磯町1−2

(0153)24‐3201

市立根室病院

日本、北海道根室市有磯町1−2

(0153)24‐3201

共愛会病院

日本、北海道函館市中島町7−21

(0138) 51-2111

元生会 森山病院

日本、北海道旭川市8条通6丁目10

(0166)22-4151

北海道療育園

日本、北海道旭川市春光台4条10丁目

(0166)51-6524

雄武町国保病院

日本、北海道紋別郡雄武町雄武1482−2

(0158)84-2517

公立芽室病院

日本、北海道河西郡芽室町東4条3丁目5

(0155)62-2811

美幌療育病院

日本、北海道網走郡美幌町字美富

(0152)73-3145

Otolaryngology/Head and Neck Surgery Study Abroad

So far, 15 members of our department have studied abroad at eight research facilities in Europe and the United States and returned to Japan. One more member began studying abroad in April 2020. Members who returned from studying abroad have made the most of the cutting-edge knowledge and techniques they acquired, achieving many results. Our department will continue to actively conduct collaborative research with overseas facilities and promote cutting-edge research.

Karolinska Institute, Stockholm, Sweden

171 77 Solna, スウェーデン

マサチューセッツ州 ハーバード大学附属ダナ・ファーバー癌研究所

450 Brookline Ave, Boston, MA 02215 アメリカ合衆国

Mayo Clinic, Arizona

アメリカ合衆国 〒85259 アリゾナ州 スコッツデール

ミネソタ州 メイヨー・クリニック

200 1st St SW, Rochester, MN 55905 アメリカ合衆国

Georgia Cancer Institute, Augusta University

Augusta University Medical Center, 1120 15th St, オーガスタ GA 30912 アメリカ合衆国

南フロリダ大学モーフィット癌センター

Moffitt USF Magnolia Campus- 12902 USF Magnolia drive Tampa, Fl Gold Valet, USF Magnolia Drive, Tampa, FL 33612 アメリカ合衆国

スイス チューリッヒ大学小児病院

スイス チューリッヒ Rämistrasse, チューリッヒ大学

Buffalo Rosewell Park Cancer Institute

665 Elm St, Buffalo, NY 14203 アメリカ合衆国

ナッシュビルヴァンダービルト大学メディカルセンター

1211 Medical Center Dr, Nashville, TN 37232 アメリカ合衆国

University of Arkansas at Little Rock

2801 South University Avenue, Little Rock, アーカンソー州 72204 アメリカ合衆国

ペンシルベニア大学医学大学院

University of Pennsylvania, Philadelphia, PA 19104 アメリカ合衆国

For students and future ENT doctors

For students and residents

787_me_f.png

A collection of our department's achievements

Collection of achievements

グループ 10.png

Classroom Introduction

Professor's Greetings

History of the classroom

Staff list

research summary

Affiliated Hospitals

Overseas related facilities

To students and those looking for training

Becoming an ENT/Head and Neck Surgeon

Recommendations for joining

Specialist Training Program

Enquiries regarding joining, training etc.

Achievements

Conference presentation

Publication

Competitive Scientific Research Funding

Thesis

Newspaper and magazine articles

Classroom Event Records

For those who wish to receive medical treatment

Treatment Overview

Medical Treatment Results

2-1-1 Midorigaoka Higashi 2-jo, Asahikawa City, Hokkaido
TEL: 0166-68-2554 FAX:0166-68-2559

To all alumni / Asahikawa Medical University Top Page / Asahikawa Medical University Alumni Association

Copyright (C) Asahikawa Medical University.

bottom of page